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Brand Name: Depakote
Classification: Fatty Acid Derivative
Available Forms: Tablet, Extended-release Tablet, Capsule, Oral Solution, Injectable (intravenous)
Target System: Central Nervous System (CNS)
Action: Increases gamma-aminobutyric acid (GABA) levels, inhibits voltage-gated sodium channels, and modulates calcium channels, leading to inhibition of excitatory neurotransmission and stabilization of neuronal activity.
Notes: Valproic acid is used for the treatment of epilepsy, bipolar disorder, and migraine prophylaxis. It requires therapeutic drug monitoring due to its narrow therapeutic index and potential for hepatotoxicity, pancreatitis, and teratogenicity.